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The Hematology research laboratory

A basic research driven by clinical challenges

Under construction, more information to be published.

Dr. Regina Michelis, PhD

Lab manager

Dr. Andrei Braester, MD

Director of the Hematology Institute at the Galilee Medical Center.

Research interests

Chemotherapy and immunotherapy

Chronic lymphocytic leukemia (CLL)

Complement-mediated-cytotoxicity (CDC)

Publications

Cell-free IgG-aggregates in plasma of patients with chronic lymphocytic leukemia cause chronic activation of the classical complement pathway

Michelis R, Tadmor T, Aviv A, Stemer G, Majdob R, Shvidel L, Shehadeh M, Barhoum M, Braester A.

PLoS One, 2020

FULL TEXT LINKS

PubMed link

A C5a-Immunoglobulin complex in chronic lymphocytic leukemia patients is associated with decreased complement activity

Michelis R, Tadmor T, Barhoum M, Shehadeh M, Shvidel L, Aviv A, Stemer G, Dally N, Rahimi-Levene N, Yuklea M, Braester A.

PLoS One, 2019

FULL TEXT LINKS

PubMed link

Free circulating active elastase contributes to chronic inflammation in patients on hemodialysis

Khatib-Massalha E, Michelis R, Trabelcy B, Gerchman Y, Kristal B, Ariel A, Sela S.

Am J Physiol Renal Physiol, 2018

FULL TEXT LINKS

PubMed link

[LEVEL AND OXIDATION OF BETA 2-MICROGLOBULIN IN HEMODIALYSIS PATIENTS TREATED WITH INTRAVENOUS IRON DURING DIALYSIS WITH HIGH-FLUX COMPARED TO LOW-FLUX DIALYZERS]

Michelis R, Sela S, Lanzmann A, Tanchilevski O, Shurtz-Swirski R, Kristal B.

Harefuah, 2017

FULL TEXT LINKS

PubMed link

In-vivo oxidized albumin- a pro-inflammatory agent in hypoalbuminemia

Magzal F, Sela S, Szuchman-Sapir A, Tamir S, Michelis R, Kristal B.

PLoS One, 2017

FULL TEXT LINKS

PubMed link

The relationship between oxidized serum albumin and blood pressure in hypoalbuminemic peritoneal dialysis patients

Hasan K, Hassan F, Michelis R.

Clin Exp Hypertens, 2017

FULL TEXT LINKS

PubMed link

Unexpected Normal Colloid Osmotic Pressure in Clinical States with Low Serum Albumin

Michelis R, Sela S, Zeitun T, Geron R, Kristal B.

PLoS One, 2016

FULL TEXT LINKS

PubMed link

The impact of oxidized serum albumin on the oncotic pressure and hydration status of peritoneal dialysis patients

Hassan K, Kristal B, Hassan F, Abo Saleh S, Michelis R.

Ther Clin Risk Manag, 2016

FULL TEXT LINKS

PubMed link